Paecilomycosis: causes, symptoms, diagnosis, and treatment

Paecilomycosis is a less common fungal infection caused by Paecilomyces, which is a conditional pathogen. Paecilomyces varioti and Paecilomyces lilacinus can cause respiratory and cutaneous infection.


Causes

The pathogens include Paecilomyces fumosoroseus, Paecilomyces heliothis, Paecilomyces javanicus, Paecilomyces manchuricum, Paecilomyces marquandii, Paecilomyces persicinus and Paecilomyces variotii.


Signs and Symptoms

Cutaneous paecilomycosis is characterized by erythema, papules, erysipelas-like redness and swelling, ulcers, or chronic granuloma caused by infection after skin trauma, which may persist for several years.

Pulmonary paecilomycosis is manifested by pneumonia or infiltrating plaques.

Invasive paecilomycosis is generally secondary infections caused by immunosuppressants after organ transplantation.


Diagnosis

The diagnosis is mainly based on the pathogens found in microscopy or histopathology.


Treatment

Imidazoles such as itraconazole, amphotericin B, and griseofulvin can be administered.