Eruptive pseudoangiomatosis: causes, symptoms, diagnosis, and treatment

Eruptive pseudoangiomatosis is a less common, spontaneously regressive disease.


Causes

The disease is caused by Echovirus 25 and 32, and it is believed that the disease is associated with EBV infection.


Signs and Symptoms

There are suddenly several, 2 - 4 mm in diameter, blanching, red papules, resembling angiomatosis, with pale halos, predominantly on the face, limbs, as well as the trunk. The eruptions persist for about 10 days in children, slightly longer in adults. Children often present with systemic symptoms of viral infection, such as malaise, fever, headache, sore throat, muscle aches, and decreased appetite, while adults often have no subjective symptoms.

Figure 1 eruptive pseudoangiomatosis


Histopathology

Superficial dermal vasodilatation and swollen vascular endothelial cells penetrating into the lumen can be seen, but there is no vascular proliferation.


Diagnosis

On the typical clinical presentations, the disease can be diagnosed.


Treatment

The disease is self-limiting and recurrent. There is not specific treatment. Symptomatic treatment may be required when there are systemic symptoms.